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Tree-man syndrome explained. The causes? CD28 deficiency!

  • Writer: DL
    DL
  • Jul 3, 2021
  • 1 min read

Our latest contribution to Cell: https://authors.elsevier.com/c/1dKmAL7PXe~pE

Another inborn error of immunity explained by Jean-Laurent Casanova's lab and colleagues.


The study of three patients with inherited CD28 deficiency, one of them having the "tree-man syndrome", reveals a narrow susceptibility to severe cutaneous HPV infection. The fact that the patients were otherwise healthy highlights the redundancy for signal 2 in T cell activation and protective immunity.



 
 
 

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Inflammation Genomics Lab

Dahdaleh Institute of Genomic Medicine

McGill University Genome Center
McGill Research Centre on Complex Traits

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© 2018 by David Langlais

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